![]() ![]() Western treatment for insomnia is based on sedatives, hypnotics, minor tranquilizers, and anxiolytics depending on the diagnosis and presentation of the patient. Lack of delta sleep can lead to chronic illness due to to toxicity and lack of rehabilitation of normal tissue function. This is the only time this occurs in adults, and most tissue repair happens during this time. secondary insomnia – due to acquired pain, anxiety and depressionĭelta sleep is a deeper level of REM during which growth hormone is secreted by the pituitary gland.primary insomnia – longstanding insomnia with an apparent relationship to a somatic or psychic event.inverted sleep pattern – sleep during the day and awake at night, common in the elderly.early morning waking – wakes several hours before the usual time.Western medicine divides sleep disorders into several different categories: ![]() This is why sleep deprivation is a torture technique in order to gain information. Interruption of REM sleep produces hyperactivity and emotionally labile behavior. Most nightmares and sleep walking and talking occur in NREM stages 3 and 4. Serotonergic pathways are implicated in NREM sleep. Norepinephrine pathways in the brainstem are implicated in REM sleep. REM always follow NREM sleep and ends each sleep cycle. Rate and depth of respiration are increased but muscle tone is depressed even lower than in NREM sleep. The EEG waves are low voltage but fast activity, and occur 5 – 6 times during a normal night’s sleep. REM ( rapid eye movement ) sleep occupies the remainder of sleep time. It is the initial phase of sleep characterized by slow EEG waves ( brain waves ), lowered respiratory and heart rates and lowered muscle tone. NREM ( non-rapid eye movement ) sleep accounts for about 75% of sleep time. All rights reserved.Insomnia and Sleep problems: Chinese and western medical approachesįrom a conventional medical point of view, there are two types and varying depths of sleep. Herbal medicine Insomnia Sleep disorders Traditional Chinese medicine. Another mechanism shown by some herbs is to upregulate the expression of orexin-A, leptin, orexin receptor-1, and leptin receptor in the brain, reducing insomnia-induced negative consequences, and thus indirectly help improvement of insomnia. Some herbs exert sedative activities via inhibition of 5-hydroxytryptamine 1A receptor. The major pharmacological action mechanisms shared by most of the sedative herbs are to act through the neurotransmitter gamma-aminobutyric acid (GABA) or via stimulation of GABAA A receptor. The underlying pharmacological action mechanisms discovered in the studies on some key herbs used in the treatment of insomnia were evaluated. Based on the clinical data, several herbs were identified as most frequently used sedative and hypnotic herbs in Chinese herbal medicine including Suanzaoren (Ziziphus spinose ), Fuling (Poria cocos ), and Gancao (Glycyrrhiza uralensis ). It was found Suanzaoren decoction (Ziziphus spinose decoction ) is the most frequently used formula for the treatment of insomnia. This brought complexity and difficulties to identify which are the essential key herbs or formulas. ![]() This was due to different syndrome patterns happened with insomnia. Clinical studies showed a very wide spectrum of herbs that were used in clinical treatment of insomnia. This chapter evaluated the data from both of clinical studies and pharmacological researches on the therapeutic formulas and on some key herbs used in the treatment of insomnia. It is very important and very helpful to review the published research papers to gather the available information for a critical analysis. Many clinical studies including randomized controlled clinical trials and research on pharmacological action mechanisms of the herbs for treatment of insomnia have been conducted. In recent decades, Chinese herbal medicine has been widely used in the Western countries. Chinese medicinal herbs and formulas have been used in the treatment of insomnia for more than 2000 years in China. Patients try to use some kinds of alternative medicines. It is effective but also has significant side effects. In conventional medicine, the most commonly used the medicine is benzodiazepine. Chronic insomnia can last for long time and it will severely affect people's health and the quality of life. Insomnia is a condition with sleep problems and many people suffered from it.
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